検索結果

Search Results for " Matrix metalloproteinases "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T5361	T-26c		MMP
	T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM).		MMP
T4783	JNJ0966		MMP
	JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).		MMP
T14978	CL-82198		MMP
	CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA). Its mechanism of action involves binding to the S1’ pocket of MMP-13, ensuring its selectiv...		MMP
T16966	S 3304		MMP
	S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.		MMP
T8961	GW280264X	Carbamic acid	MMP
	GW280264X (Carbamic acid) is an inhibitor of ADAM17 .		MMP
T2009	SB-3CT		MMP
	SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).		MMP
T5416	T-5224		MMP
	T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors.		MMP
T16124	MMP13-IN-3		MMP
	MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis.		MMP
T22115	SM-7368		NF-κB
	The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.		NF-κB
T14322	ARP-100	MMP-2 Inhibitor III	MMP
	ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion ...		MMP
T5983	O-Phenanthroline	1,10-Phenanthroline	MMP , Others
	o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene m...		MMP , Others
T6011	Batimastat	BB94	MMP
	Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis.		MMP
T1891	NSC 405020		MMP
	NSC 405020 is a noncatalytic inhibitor of MT1-MMP.		MMP
T8310	MMP-9-IN-1		MMP
	MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).		MMP
T7522	GI254023X	GI 254023X	MMP , Immunology/Inflammation related
	GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis...		MMP , Immunology/Inflammation related
T4282	S-methyl-KE-298		MMP , Drug Metabolite
	S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.		MMP , Drug Metabolite
T2743	Ilomastat	Galardin,GM6001	MMP
	Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.		MMP
T6009	TAPI1	TAPI 1,TAPI,TAPI-1	MMP
	TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.		MMP
T21806	HNHA		HDAC
	HNHA is an inhibitor of HDAC.		HDAC
T0407	Edaravone	MCI-186	Apoptosis , MMP , Free radical scavengers
	Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.		Apoptosis , MMP , Free radical scavengers
T15574	Incyclinide	COL-3,CMT-3	MMP
	Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.		MMP
T7459	Abametapir	HA-44,BRN 0123183	MMP , Others , Parasite
	Abametapir (BRN 0123183), a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.		MMP , Others , Parasite
T6885	Marimastat	BB2516,KB-R8898,TA2516	MMP
	Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM).		MMP
T7449	O-Phenanthroline monohydrate	Phenanthroline monohydrate,1, 10-Phenanthroline monohydrate	MMP
	o-Phenanthroline monohydrate (1, 10-Phenanthroline monohydrate) is an inhibitor of metallopeptidases, inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. subtilis neutral protease and B. thermoproteolyticus thermo...		MMP
T6542	Imidapril hydrochloride	Novaloc,Imidapril HCl,Tanapril,TA-6366	RAAS
	Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.		RAAS
T5863	Indinavir sulfate	L735524 sulfate,MK-639 sulfate	SARS-CoV , HIV Protease
	Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.		SARS-CoV , HIV Protease
T1140	Doxycycline hydrochloride	Doxylin,Vibramycin,Hyclate	MMP , Antibacterial , Antibiotic
			MMP , Antibacterial , Antibiotic
T22962	Mca-Pro-Leu-NH2		Others
	Substrate of matrix metalloproteinases assay		Others
TP1741L	Histatin 5 acetate	Histatin 5 acetate (115966-68-2 Free base)	MMP
	Histatin 5 acetate inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.		MMP
T61271	MMP2-IN-3		MMP
	MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM). MMP2-IN-3 inhibits MMP-9 and MMP-8 with IC50s of 26.6 and 32 μM, respectively.		MMP
TP1501L	CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)		MMP
	CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, an...		MMP
T69503	ABT-518
	ABT-518 is an inhibitor of matrix metalloproteinases, which are associated with tumor growth and development of metastasis.
T27507	GW-3333	GW 3333,GW3333
	GW-3333 is an matrix metalloproteinase inhibitor. It is also a tumor necrosis factor-alpha (TNF)-Converting Enzyme (TACE) inhibitor. The efficacy of GW3333 suggests that dual inhibitors of matrix metalloproteinases and T...
T26104	Ro 28-2653	Ro 28 2653,Ro-28-2653,Ro282653
	Ro 28-2653 is a matrix-metalloproteinases (MMPs) inhibitor with high selectivity for MMP2, MMP9 and membrane type 1-MMP.
T24431	Matlystatin A
	Matlystatin A is an inhibitor of aminopeptidase. It shows multiple inhibitory activities against both aminopeptidase N and matrix metalloproteinases.
T13358	XL-784		MMP
	XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).		MMP
T70052	S-3304
	S-3304 is a n orally-agent agent with potential antineoplastic activity. S-3304 inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and ...
T25055	Alpha-RA-F	α RA F,alphaRAF,α-RA-F,αRAF
	alpha-RA-F can modulate collagen synthesis and matrix metalloproteinases (MMPs) expression levels by boosting collagen synthesis and reducing MMPs expression levels in human fibroblasts without cytotoxicity.
T16986	Tanomastat	BAY 12-9566	MMP
	Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively.		MMP
T13357	XL-784 free base		Others
	XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP), (IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).		Others
T75755	Histatin 5 TFA
	Histatin 5 TFA effectively inhibits host matrix metalloproteinases (MMP-2) and (MMP-9), demonstrating inhibition concentrations (IC 50s) of 0.57 μM and 0.25 μM, respectively.
TP1741	Histatin 5
	Histatin 5 inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. Histatin 5 is a human basic salivary peptide with strong fungicidal properties in vitro...
T76017	CTTHWGFTLC, CYCLIC TFA
	CTTHWGFTLC, also known as CYCLIC TFA, is a cyclic peptide that acts as an inhibitor of matrix metalloproteinases (MMP-2 and MMP-9), with an IC50 value of approximately 8 μM for MMP-9 [1].
T81728	Myristoyl tetrapeptide Ala-Ala-Pro-Val
	Myristoyl tetrapeptide Ala-Ala-Pro-Val is a bioactive peptide that stimulates the expression of extracellular matrix (ECM) proteins and inhibits the expression of metalloproteinases (MMPs).
T71420	RO314724
	RO314724 is a HDAC inhibitor. RO314724 is also a a reversible, tightly binding, MMP inhibitor with a Ki of 26 nm. Matrix metalloproteinases (MMPs) belong to the key enzymes of the proteolytic destruction of cartilage m...
TP1501	CTTHWGFTLC, CYCLIC
	This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic interven...
TP1446	Histatin 5 (TFA)(115966-68-2,free)	Histatin 5 (TFA)	MMP
	Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.		MMP
T14312	Apratastat		MMP , TNF
	Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitr...		MMP , TNF
T21814	ONO 4817
	ONO-4817 is a broad-spectrum matrix metalloproteinase (MMP) inhibitor that potentially mitigates atherosclerotic neointimal proliferation and atheromatous plaque progression by suppressing matrix metalloproteinases (MMPs...
T60551	MMP2-IN-2
	MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC 50 of 4.2 μM. It also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC 50 values of 12, 23.3, ...

Compounds

Synonym: Carbamic acid

Synonym: MMP-2 Inhibitor III

Target: MMP

o-Phenanthroline

T5983

Synonym: 1,10-Phenanthroline

Target: MMP, Immunology/Inflammation related

S-methyl-KE-298

T4282

Synonym:

Target: MMP, Drug Metabolite

Ilomastat

T2743

Synonym: Galardin,GM6001

Target: MMP

TAPI1

T6009

Synonym: TAPI 1,TAPI,TAPI-1

Target: Apoptosis, MMP, Free radical scavengers

Synonym: HA-44,BRN 0123183

Target: MMP, Others, Parasite

Marimastat

T6885

Synonym: BB2516,KB-R8898,TA2516

Target: MMP

o-Phenanthroline monohydrate

T7449

Synonym: Phenanthroline monohydrate,1, 10-Phenanthroline monohydrate

Target: MMP

Imidapril hydrochloride

T6542

Synonym: Novaloc,Imidapril HCl,Tanapril,TA-6366

Target: RAAS

Indinavir sulfate

T5863

Synonym: L735524 sulfate,MK-639 sulfate

Target: SARS-CoV, HIV Protease

Doxycycline hydrochloride

T1140

Synonym: Doxylin,Vibramycin,Hyclate

Target: MMP, Antibacterial, Antibiotic

Synonym: Histatin 5 acetate (115966-68-2 Free base)

CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)

Synonym: GW 3333,GW3333

Target:

Ro 28-2653

T26104

Synonym: Ro 28 2653,Ro-28-2653,Ro282653

Synonym: α RA F,alphaRAF,α-RA-F,αRAF

CTTHWGFTLC, CYCLIC TFA

T76017

Synonym:

Target:

Myristoyl tetrapeptide Ala-Ala-Pro-Val

Histatin 5 (TFA)(115966-68-2,free)

TP1446

Synonym: Histatin 5 (TFA)

カタログ番号	製品名	別名	ターゲット
T3414	Morroniside		Apoptosis , MMP , Pyroptosis
	Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib...		Apoptosis , MMP , Pyroptosis
T2993	Cordycepin	3'-Deoxyadenosine	MMP , TNF , Antibacterial , Antibiotic , Autophagy
	Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity.		MMP , TNF , Antibacterial , Antibiotic , Autophagy
T4115	Auraptene	7-geranyloxycoumarin	MMP , BACE
	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...		MMP , BACE
TN1879	Lucideric acid A	Lucidenic acid A	MMP , p38 MAPK , JNK
	Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation.		MMP , p38 MAPK , JNK
T3860	Isoliquiritin apioside		MMP , p38 MAPK , NF-κB
	Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse...		MMP , p38 MAPK , NF-κB
T2967	Stigmasterol	Stigmasterin,beta-Stigmasterol	MMP , Endogenous Metabolite
	Stigmasterol (Stigmasterin) is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol has been focused on the ch...		MMP , Endogenous Metabolite
T8259	Doxycycline monohydrate		MMP , Antibacterial , Antibiotic , Parasite
	Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)		MMP , Antibacterial , Antibiotic , Parasite
T6S0444	Salvianolic acid A	Dan Phenolic Acid A	MMP
	Salvianolic acid A (Dan Phenolic Acid A) could protect the blood brain barrier through inhibition of matrix metallopeptidase 9 (MMP-9) and anti-inflammation.		MMP
T2957	Arctigenin	(-)-Arctigenin	Apoptosis , MMP , Influenza Virus , Autophagy
	(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plan...		Apoptosis , MMP , Influenza Virus , Autophagy
T3767	Polygalacic acid	Virgaureagenin G	MMP , AChR , AChE
	Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva...		MMP , AChR , AChE
T2980	Chondroitin sulfate	Chonsurid,Chondroitin polysulfate	MMP , Others , Endogenous Metabolite , NO Synthase
	Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition		MMP , Others , Endogenous Metabolite , NO Synthase
T3S0640	Triolein	Glycerol trioleate,Glycerine Trioleate	MMP , Others , Endogenous Metabolite
	Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.		MMP , Others , Endogenous Metabolite
T5S1026	Apigenin-7-glucuronide	Apigenin 7-O-glucuronide	MMP
	Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit MMP activities (IC50s: 12.87, 22.39, 1...		MMP
T5680	Aloin(mixture of A&B)		MMP , IL Receptor , Antibacterial , Antifungal
	ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.		MMP , IL Receptor , Antibacterial , Antifungal
T2987	(-)-Epigallocatechin	l-Epigallocatechin,Epigallocatechin,EGC	MMP , Autophagy
	(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting their transformation into amyloid fibrils.		MMP , Autophagy
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
T2750	Ginkgolide C	BN-52022	MMP , Sirtuin , Endogenous Metabolite , AMPK
	Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.		MMP , Sirtuin , Endogenous Metabolite , AMPK
T6S2140	β-Anhydroicaritin	Anhydroicaritin,Beta-Anhydroicaritin	MMP , Others , TNF , Interleukin
	1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turnover induced by ovariectomy, improve BMD the biomechanical ...		MMP , Others , TNF , Interleukin
T3850	Luteolin 7-O-glucuronide	Luteolin-7-glucuronide	MMP
	Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) possesses antioxidant activities.		MMP
T5S0045	Isofraxidin	6,8-Dimethoxyumbelliferone,Phytodolor	MMP , ERK , p38 MAPK , TLR , COX
	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...		MMP , ERK , p38 MAPK , TLR , COX
T1687	Doxycycline	Vibramycin,Doxiciclina,Doxytetracycline,Doxycyclinum	MMP , ribosome , Antibacterial , Antibiotic , Parasite
	Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.		MMP , ribosome , Antibacterial , Antibiotic , Parasite
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
T3813	20(R)-Ginsenoside Rh2	(20R)Ginsenoside Rh2,Ginsenoside Rh2	Apoptosis , MMP , HSV
	20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.		Apoptosis , MMP , HSV
T1687L	Doxycycline (hyclate)	Doxycycline hydrochloride hemiethanolate hemihydrate,WC2031,Doxycycline hyclate	MMP , ribosome , Antibacterial , Antibiotic
	Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor act...		MMP , ribosome , Antibacterial , Antibiotic
T1205	Chloramphenicol	Chlornitromycin,Levomycetin,Chloromycetin	ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
T2769	3-Aminopropionitrile fumarate (2:1)	Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate	Others
	3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) is an organic compound and antirheumatic agent used in veterinary medicine.		Others
TN2697	2,3-Dihydrohinokiflavone		MMP , Parasite , Antifection
			MMP , Parasite , Antifection
TN4088	Futoenone		PAFR
	Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases, the molecular modelings of these compounds indicate the preferred binding of the P2' site of the enzymes. Neol...		PAFR
TN4592	Murrangatin		IL Receptor , TNF , COX , Prostaglandin Receptor
	Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity ag...		IL Receptor , TNF , COX , Prostaglandin Receptor

天然物製品

Morroniside

T3414

Synonym:

Target: Apoptosis, MMP, Pyroptosis

Cordycepin

T2993

Synonym: 3'-Deoxyadenosine

Target: MMP, TNF, Antibacterial, Antibiotic, Autophagy

Auraptene

T4115

Synonym: 7-geranyloxycoumarin

Target: MMP, BACE

Lucideric acid A

TN1879

Synonym: Lucidenic acid A

Target: MMP, p38 MAPK, JNK

Isoliquiritin apioside

T3860

Synonym:

Target: MMP, p38 MAPK, NF-κB

Stigmasterol

T2967

Synonym: Stigmasterin,beta-Stigmasterol

Target: MMP, Endogenous Metabolite

Doxycycline monohydrate

T8259

Synonym:

Target: MMP, Antibacterial, Antibiotic, Parasite

Salvianolic acid A

T6S0444

Synonym: Dan Phenolic Acid A

Target: MMP

Arctigenin

T2957

Synonym: (-)-Arctigenin

Target: Apoptosis, MMP, Influenza Virus, Autophagy

Polygalacic acid

T3767

Synonym: Virgaureagenin G

Target: MMP, AChR, AChE

Chondroitin sulfate

T2980

Synonym: Chonsurid,Chondroitin polysulfate

Target: MMP, Others, Endogenous Metabolite, NO Synthase

Triolein

T3S0640

Synonym: Glycerol trioleate,Glycerine Trioleate

Target: MMP, Others, Endogenous Metabolite

Apigenin-7-glucuronide

T5S1026

Synonym: Apigenin 7-O-glucuronide

Target: MMP

Aloin(mixture of A&B)

T5680

Synonym:

Target: MMP, IL Receptor, Antibacterial, Antifungal

(-)-Epigallocatechin

T2987

Synonym: l-Epigallocatechin,Epigallocatechin,EGC

Target: MMP, Autophagy

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

Ginkgolide C

T2750

Synonym: BN-52022

Target: MMP, Sirtuin, Endogenous Metabolite, AMPK

β-Anhydroicaritin

T6S2140

Synonym: Anhydroicaritin,Beta-Anhydroicaritin

Target: MMP, Others, TNF, Interleukin

Luteolin 7-O-glucuronide

T3850

Synonym: Luteolin-7-glucuronide

Target: MMP

Isofraxidin

T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,Phytodolor

Target: MMP, ERK, p38 MAPK, TLR, COX

Doxycycline

T1687

Synonym: Vibramycin,Doxiciclina,Doxytetracycline,Doxycyclinum

Target: MMP, ribosome, Antibacterial, Antibiotic, Parasite

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: MMP, Others

20(R)-Ginsenoside Rh2

T3813

Synonym: (20R)Ginsenoside Rh2,Ginsenoside Rh2

Target: Apoptosis, MMP, HSV

Doxycycline (hyclate)

T1687L

Synonym: Doxycycline hydrochloride hemiethanolate hemihydrate,WC2031,Doxycycline hyclate

Target: MMP, ribosome, Antibacterial, Antibiotic

Chloramphenicol

T1205

Synonym: Chlornitromycin,Levomycetin,Chloromycetin

Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

3-Aminopropionitrile fumarate (2:1)

T2769

Synonym: Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate

Target: Others

2,3-Dihydrohinokiflavone

TN2697

Synonym:

Target: MMP, Parasite, Antifection

Target: IL Receptor, TNF, COX, Prostaglandin Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain)	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPK-01286	MMP-8 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance o...
TMPK-00093	TIMP-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation an...
TMPH-02106	SH3PXD2A Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides...
TMPJ-00101	TIMP-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the...
TMPJ-00916	TIMP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP...
TMPH-02285	USP6 Protein, Human, Recombinant (His & KSI)	Human	E. coli
	Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activit...
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His)	Human	HEK293 Cells
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ...
TMPJ-00362	MMP-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metallo...
TMPY-04100	MMP-26 Protein, Human, Recombinant	Human	E. coli
	MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene. MMP26 is a member of matrix metalloproteinases (MMPs) and has been reported to be highly expressed in many cancers. The protein differs from most MMP family me...
TMPY-02954	ADAMTSL1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	ADAMTSL1 is a secreted molecule resembling members of the ADAMTS protein family of matrix metalloproteinases. Both ADAMTS proteins and ADAM protein family contain a disintegrin and a metalloprotease domain. Metallospondi...
TMPJ-00957	MMP-9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of s...
TMPJ-00159	EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermato...
TMPY-02404	ADAM9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various ...